Major stock markets in the United States traded with slight losses in the premarket on Wednesday after yesterday's bleak consumer confidence report. Today's economic data schedule includes the weekly mortgage applications release and durable goods orders for February, along with speeches from several Federal Reserve officials.

The Dow Jones lost 0.13% at 4:23 am ET, the Nasdaq 100 declined by 0.19% and the S&P 500 dropped 0.16%.

The euro traded flat against the dollar and went for 1.07888 at 4:24 am ET.